PC5936 has found new applications as a blocking group. It has been utilized to prepare blocked derivatives of hydroxy compounds. Derivatization of substrates is accomplished efficiently in DMF containing a slight molar excess of imidazole. Blocked intermediates exhibited acidic hydrolytic stability intermediate between that of a PC8710(Tert-butyldimethylchlorosilane) and PC8710(Tert-butyldiphenyl chlorosilane) derivatives. Greater stability was obtained with PC5936 under basic conditions.
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